Regulatory enzyme overexpression may protect against neurodegeneration in Huntington’s disease.

Treatment that increases brain levels of an important regulatory enzyme may slow the loss of brain cells that characterizes Huntington’s disease (HD) and other neurodegenerative disorders. In a report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital (MGH)-based research team reports that increased expression of Sirt1, one of a family of enzymes called sirtuins, in the brain of a mouse model of HD protected against neurodegeneration. They also identified a potential mechanism for this protective effect.

Read more about this exciting research:

http://medicalxpress.com/news/2011-12-regulatory-enzyme-overexpression-neurodegeneration-huntington.html

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About UWF Center on Aging

The Center on Aging at the University of West Florida was established in the Fall of 2010 when the School of Psychological and Behavioral Sciences faculty along with assistance from Sponsored Research submitted a grant to the State University System Board of Governors in support of aging initiatives for Northwest Florida. Its mission is to improve the quality of life of aging adults through the application of science to address challenges associated with aging and to promote healthy aging, with an emphasis on prevention. This will be accomplished through inter-disciplinary and inter-professional efforts of basic and applied research, consultation, and partnerships with community agencies. Education and training, direct services to the aging population, and public awareness and understanding of the contributions and needs of elders will be primary objectives.
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2 Responses to Regulatory enzyme overexpression may protect against neurodegeneration in Huntington’s disease.

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